Main ingredient in over-the-counter decongestants does not work, FDA panel guidelines

The important thing ingredient in in style decongestants resembling Sudafed PE, Benadryl Allergy Plus Congestion and Allegra-D does not relieve nasal congestion when taken orally, a Meals and Drug Administration (FDA) panel concluded in a gathering Tuesday (Sept. 12).

After reviewing years’ value of information, the FDA’s Nonprescription Drug Advisory Committee (NDAC) discovered that the effectiveness of the decongestant ingredient, phenylephrine, may help relieve a stuffy nostril when delivered straight into the nostril — by way of a nasal spray, for instance — however does not work when taken by mouth, the 16 panelists unanimously determined. 

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